audioIn an astonishing story of a scientific discovery, Greg Winter tells Jim Al-Khalili how decades of curiosity-driven research led to a revolution in medicine. Forced to temporarily abandon his work in the lab when a road rage incident left him with a paralysed right arm, Greg Winter spent several months looking at the structure of proteins. Looking at the stunning computer graphics made the pain in his arm go away. It also led him to a Nobel Prize winning idea: to ‘humanise’ mouse antibodies. A visit to an old lady in hospital made Greg determined to put his research to good use. He fought hard[...]
audioSue Black left home and school when she was 16. Aged 25, she attended an access course to get the qualifications she needed to go to university to study computer science. It was a bit lonely being the only student in a mini- skirt surrounded by a sea of suits, but she came top of the class nonetheless. She signed up to do a PhD (not really knowing what a PhD was) and worked on the ripple effect in software. What happens when you change one bit of code? Does it mess up everything else? A lot of new software is created by building on and adapting existing programmes so these are important [...]
audioIn an ideal (quantum) world, Jim Al-Khalili would be interviewing himself about his life as a scientist but since the production team can’t access a parallel universe, Adam Rutherford is stepping in to ask Jim questions in front of an audience at The Royal Society. Jim and his family left Iraq in 1979, two weeks before Saddam Hussein came to power, abandoning most of their possessions. Having grown up listening to the BBC World Service, he had to drop his ts to fit in at school in Portsmouth where he was one of just three boys in a class of more than a hundred girls. He specialised in nuclear[...]
audioJim Al-Khalili talks to astronomer Jocelyn Bell Burnell.
Jocelyn Bell Burnell forged her own path through the male-dominated world of science - in the days when it was unusual enough for women to work, let alone make a discovery in astrophysics that was worthy of a Nobel Prize.
As a 24-year old PhD student, Jocelyn spotted an anomaly on a graph buried within 100 feet of printed data from a radio telescope. Her curiosity about such a tiny detail led to one of the most important discoveries in 20th century astronomy - the discovery of pulsars - those dense cores of collapsed sta[...]
audioClive Oppenheimer has, more than once, been threatened with guns (a Life Scientific first?). He's dodged and ducked lava bombs and he's risked instant death in scorching and explosive eruptions.
He studies volcanoes; science that by necessity, requires his presence at the volcanic hotspots of the world. It was at the lip of a bubbling lava crater on one of the earth's most active volcanoes, Mount Erebus in Antarctica, that he met the film and documentary maker Werner Herzog. The two became friends and went on to make a volcano movie together. Clive, who's Professor of Volcanology at the Unive[...]
audioMaggie Aderin-Pocock has been fascinated by space since she was a young child. When she was six years old she caught the bug when she saw a picture of an astronaut on the front of a book in her primary school library. As a teenager she built her own telescope.
After studying physics and mechanical engineering, Maggie worked in industrial research before returning to her first love, astronomy, when she managed the building of an instrument on a giant telescope in Chile. Now, she spends her time presenting TV programmes, in particular the BBC’s Sky at Night, and inspiring the next generation [...]
audioAlastair Hay, now Emeritus Professor of Environmental Toxicology at the University of Leeds, is a chemist who’s had a dual career as an academic researcher and an outspoken activist and campaigner. The common theme has been the application of his knowledge to how chemicals affect our lives, in the workplace and during conflicts. Alastair Hay is best known for his work to rid the world of chemical weapons, a concern about this horrific form of warfare that goes back to the use of Agent Orange in the Vietnam War. His work culminated in the Chemical Weapons Convention, which came into force in [...]
audioHow do you convince Formula One racing drivers that they are speeding round the race track at Le Mans when, in fact, they are sitting in a simulator in the McLaren offices in Woking? Apparently it’s all about getting the vibrations right. Racing drivers really do drive by the seat of their pants. They’re also highly attuned to the sound f the engine and instinctively associate different sounds with different speeds. When Caroline Hargrove started trying to build a driveable model of a Formula One car many thought it just wouldn’t be possible. Today, all the major manufacturers of Formula One [...]
audioWhen Michael Stratton was a young doctor he would diagnose cancer by studying tissue samples under a microscope. However, over the past 30 years he’s been advancing our understanding of this disease down at the level of the genes themselves, so that we are now able to read the DNA of a cancer. This had led to new diagnoses and treatments.
Mike Stratton’s first foray into genetics culminated in the discovery of the BRCA 2, one of the main genes involved in hereditary breast cancer. Following this painstaking detective work he and the Institute for Cancer Research became embroiled in a patent [...]
audioSuzanne O'Sullivan has been described as “a detective of the mind”. She’s a neurologist who helps some patients with the strangest of symptoms, from so-called ‘Alice in Wonderland’ seizures to those suffering from temporary blindness or paralysis, and that turn out to originate in their subconscious minds.
By the time these people get to see Dr Suzanne O’Sullivan they’ll often have been to many specialists, undergone a range of tests and given a variety of diagnoses. Suzanne’s an expert on epilepsy, and the unusual ways that seizures can manifest themselves, who currently works at University C[...]
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